Pediatric Apert syndrome symptoms and treatment
Patients with Apert syndrome can have related health and developmental issues, reinforcing the need for coordinated, multidisciplinary care and access to a variety of pediatric subspecialists. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We only use quality, credible sources to ensure content accuracy and integrity. This may include therapy to help a child and their family to cope with the daily challenges of this syndrome. A child with Apert syndrome will require life-long observations and checkups. This protein has many important roles in a fetus’ development, including a key role in signaling bone cell development.
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- Symptoms of Apert syndrome are similar to other conditions as a result of the baby’s skull bones fusing together too soon (craniosynostosis) during fetal development.
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- As a result, your baby’s skull, face, hands and feet show distinct characteristics that diagnose the condition, including webbed fingers and toes and having a broad and tall forehead.
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Finger separation surgery begins between 9 and 12 months of age, with a second stage following about three months later. The goal is to release the fused sutures and reshape the skull to allow the brain adequate room to grow. These problems are manageable with treatment, but they need to be monitored from early in life.
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The Microsoft 365 Copilot app lets you create, share, and collaborate all in one place with innovative apps. Watch our educational video to learn more about the services and treatment options CHOP offers to children with craniofacial conditions such as Apert syndrome. Additionally, our Craniofacial Team maintains close collaboration with Genetics, Ophthalmology, Speech, Otolaryngology (ENT), Audiology and Neurosurgery to help provide comprehensive craniofacial care. At CHOP, our experienced Craniofacial Surgeons will help guide your child through craniosynostosis repair and other surgeries to address symptoms related to airway, dental/jaw relationships and craniofacial relations. The treatment of Apert syndrome is dependent upon both functional and appearance-related needs, and should be addressed immediately after your child is born.
Craniofacial treatments
Apert syndrome is a genetic disorder that causes abnormal head and face growth, as well as fused fingers and toes. Because Apert syndrome affects so many body systems, no single specialist can manage it alone. Dental and orthodontic treatment runs alongside these procedures, monitoring tooth eruption and guiding jaw alignment. Eye muscle surgery to correct misalignment is usually done after the final positioning of the eye sockets. Midface surgery, which advances the underdeveloped central face forward to improve breathing, appearance, and bite alignment, is typically delayed until age 6 to 8.
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If you have a history of Apert syndrome in your family and you are planning on becoming pregnant, talk with your healthcare provider about genetic counseling to identify any potential risks as you grow your family. Symptoms of Apert syndrome are similar to other conditions as a result of the baby’s skull bones fusing together too soon (craniosynostosis) during fetal development. If you are planning on becoming pregnant, talk with your healthcare https://ballonixapp.net/ provider about genetic testing to see if you are at risk of passing certain genes onto your child. Your child may need follow-up surgery as they develop to target any persistent symptoms of the condition. Close follow-up with multiple specialists is necessary for your baby.
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Apert Syndrome Symptoms
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Craniosynostosis occurs, in which the cranial sutures close too soon, though the child’s brain is still growing and expanding. In the case of acrocephalosyndactyly, selective cell death does not occur and skin, and rarely bone, between the fingers and toes fuses. Disturbances in the development of the branchial arches in fetal development create lasting and widespread effects. The Craniofacial Program at Boston Children’s incorporates all of these specialists to care for more than 500 patients every year who have a range of craniofacial diagnoses. Fused fingers and toes distinguish Apert syndrome from other craniofacial disorders. The FGFR2 gene is also involved in similar craniofacial syndromes, including Crouzon syndrome, Pfeiffer syndrome, and Jackson-Weiss.